Estrogenics (The Cause)

Definition of Estrogenic

A class of chemicals in our everyday environment that, when absorbed, ingested or consumed — produce “estrogen-like” effects inside the cells, wreaking havoc on all body systems

THE 10 CATEGORIES

  • Phytoestrogens – Plants, Soy, Flax, Lavender, Cannabis
  • Mycoestrogens – Mold, Fungus, Grains
  • Atrazine – Herbicide on all non-organic crops
  • Triclosan & APE’s – Soaps and Cleaning Products
  • BP & 4MBC – Sunscreen - Benzophenone and Methylbenzyldine Camphor
  • Red 3 and 40 - Food Additives and Coloring
  • Parabens – Fragrances
  • Phthalates – Plastic Additives
  • BPA, BPS – Plastic Ingredient
  • EE2 – Birth Control – Ethinylestradiol

PHYTOESTROGENS

  • SOY – Soy activates the opiod receptor that morphine, heroin abnd endorphins activate
  • LAVENDER – Prepubertal gynomastia (man boobs)

FOODS TO AVOID

TOP 2 producers in the study of COUMESTAN, ISOFLAVONES, LIGNANS

  • FLAXSEED – 380,000 ug
  • SOYBEANS – 100,000 ug
  • Soy Protein – 8800 ug phytoestrogens
  • Sesame Seed – 8000 ug

LIGNANS

  • Lignans decrease free testosterone (from 1980s studies)
  • Lignans are created by plants as a protective measure so they are not eaten in the wild

Soy

Isoflavones developmental toxicity, estrogenic development carcinogenis (cancer), goiter

  • Increased risks of soy:
  • Increased risk of breast cancer
  • Male hormonal and fertility problems
  • Hypothyroidism
  • Anti-nutrient content
  • STUDY - Soy caused weight gain in rats and increased fat in offspring

MYCOESTROGENS

FOODS TO AVOID

  • Molds
  • Yeasts
  • Cereals
  • Corn
  • Soybeans
  • Grains
  • Cheap coffee
  • Cheap chocolate

    • ZEA – Zearalenone

    • 16 countries have limits on it
    • Russia bans it – since 2001 – no more than 1000 micrograms per kilogram
    • Europe – limits to 20-350ug/kg
    • ZEAs are stored in fat…less in birds and more in pigs which are fattier
    • ZEA intentionally used to fatten cattle
    • ZEA contributes to early puberty for children

    Effects of ZEA, Zearalenone

    • Liver tumor formations
    • Brain problems
    • Impairment of male reproductive system
    • Hepatotoxic
    • Haematotoxic
    • Immunotoxic
    • Genotoxic

    ATRAZINE

    • Europe banned Atrazine use on crops since 2004
    • 2nd most popular chemical next to glyphosate
    • 80 million pounds of production per year

    Effects of Atrazine

    • Chemically castrates frogs in tiny doses
    • Endocrine disruptor
    • Causes birth defects in people
    • Developmental toxicity in mice
    • Increases rates of specific hernias
    • Low doses causes chemical abortions in mice

    Mercury and Atrazine connection

    • Added as a preservative in herbicides, fungicides, pesticides, kills bacteria and other microorganisms and brain cells
    • China uses 10M lbs of atrazine on their fields in 2012
    • Why do they use it?
    • Long Shelf Life and doesn’t break down - similarly it doesn’t break down in the human body.

    How Long Atrazine Lasts in Soil

    • Half life in soil – 77 degrees
    • 315 in red soil
    • 165 days in brown soil
    • 248 days in black soil

    LIMITS OF ALLOWABLE ATRAZINE IN WATER

    • 3000ug/kg is maximum allowable limit in drinking water
    • 2013 – 2-3 million people are readily exposed to atrazine in drinking water at 200ng/dl
    • 80% of lakes in Texas have high levels of atrazine
    • 95% of Minnesota bodies of water had high levels of atrazine
    • 5% of all raw water in the US has Atrazine levels more than 4800ug/kg
    • 1% of RAW WATER was at 34,000ug/kg – 170x the amount that completely destroys a frog’s genitals, turning males into females
    • 5% of DRINKING WATER was at 2700ug/kg
    • 1% at 22,700ug/kg – 114x the amount that completely destroys a frogs genitals, turning males into females
    • The European Union completely bans the use of atrazine on their crops

    REPRODUCTIVE ABNORMALITIES

    • 200ng/L has been demonstrated to cause reproductive abnormalities in frogs – absorbing it via skin and the eggs that sit outside the body in water polluted with Atrazine

    ATRAZINE FACTS

    • Atrazine does not break down in water – loves fat, seeks fat
    • Overlap in areas where Atrazine is sprayed heavily and obesity prevalence maps (causal relationship)
    • Rats treated with water and low concentrations of atrazine found:
    • Mitochondrial functions were disrupted and rats developed diabetes

    TRICLOSAN & APEs (Alkylphenols)

    APE’s

    • Surfectants in soap and detergents which cause suds to form
    • They are not present in labels
    • No legal ramifications to show they are in products

    Triclosan

    • Found in many soaps
    • Triclosan and BPAs - estrogenic properties and similar chemical structures

    LEGALITY OF TRICLOSAN

    • EUROPEAN UNION banned them entirely
    • Even CHINA added certain APEs to severly toxic list in 2011
    • UNited States allows them

    EFFECTS OF EXPOSURE

    • Subcutaneous abortion accompanied by decline of estrogen sulfotransferase activity in humans and mice
    • APES transfer from mother to child in utero
    • Leading to implantation failure
    • Pregnancy loss or ther complications
    • Altered genes in fish (2 weeks after) just a single day exposure to APEs
    • Stored in fat, particularly the brain, potential modulators of the allergic response

    AVOID

    • Paints
    • Adhesives
    • Inks
    • Washing agents
    • Pesticides
    • Textiles
    • Detergents
    • Leathers
    • Pulp at paper mill
    • Brown restroom paper towels

    BP & 4MBC

    Benzophenone in SUNSCREEN

    • Avoid anything with BENZ in it
    • Avoid anything with PHEN in it

    LEGALITY

    • 4 MBC – Banned in Europe in 2015
    • Benzophenone is Allergen of the year in the US and it is still not banned
    • Both stick to estrogen receptors

    PARADOX - IT ACTUALLY CAUSES SKIN CANCER

    • UV light from the sun is capable of fully fusing 4MBC or BP to estrogen receptors
    • The UV light from the sun is essentially apable of GLUING the sunscreen estrogenics to the estrogen receptor
    • This turns the estrogen receptor to ON position far longer than normal, causing longer term damage
    • It would be ironic if BP and 4MBC accelerate aging process as well

    Effects of 4MBC

    • Pituitary effects comparable to hypothyroidism
    • Endometriosis
    • Accumulates in fat

    RED 3 and 40 Food Dyes and Coloring

    • 1997 - RED No. 3 – Estrogenic and DNA damaging activity of REd NO. 3 in human breast cancer cells
    • Watch for phenosulfothiazine or phenothiazine

    LEGALITY

    • RED 40 – UK Europe all legal with label warning of dangers
    • US -legal with no warnings
    • JAPAN – BANNED
    • SWITZERLAND – BANNED

    UNITED STATES REGULATIONS - NONE

    • Can be used in food/drink but not cosmetic
    • 26 attempts to make Red 3 banned

    EFFECTS

    • Major toxic manifestations
    • Central nervous system depression
    • Inhibits dopamine uptake into brain synaptosamal preparations
    • Increased hyperactivity in 3 year old and 8/9 year olds
    • Linked with ADHD hyperactivity

    PARABENS

    • They bind estrogen receptor
    • Alter thyroid hormone levels during pregnancy
    • May contribute to brain physiopathology in autism spectrum disorder
    • Increase anxiety
    • Parabens pass through the blood brain barrier of seals (presumably humans too)
    • Presence in human fat cells: 17,400ng/g

    FETAL EXPOSURE

    • Fetal exposure to parabens – endocrine disrupting potential and possible impact on fetal development
    • Parabens in human umbilical cord blood
    • In over 40% of the samples

    LEGALITY

    • European Union (EU) has banned benzylparaben and phenylparaben and 3 more from all cosmetics
    • United States has no regulations

    PHTHALATES

    • Most common toxin humans are exposed to on a daily basis
    • US infants far exceeded EPAs maximum levels in blood tests in 2014
    • Association between phthalates levels in urine and breast cancer (Alaskan natives and non natives to Alaska)

    FOUND IN:

    • Cooking oils
    • Dairy products
    • Heating food in plastics in microwave
    • PVC
    • Personal care products
    • Perfumes
    • Medical devices
    • Printing and ink coatings
    • Childrens toys
    • Pharma drugs
    • Textiles
    • Food products
    • Shower curtains
    • Floor tiles
    • Cleaning materials
    • Food containers
    • Wrappers
    • Vinyl flooring
    • Crib mattresses
    • CLEAR PLASTICS - They increase CLARITY of plastics (making them clearer, flexible and durable)

    PRODUCTION

    • 300 billion lbs per year globally
    • China and india produce the most but refuse to show their numbers

    LEGALITY

    • 2015 – EU adds to banned or restricted list
    • NO BAN IN United States
    • Restricts some presence in child’s toys, but nothing more

    ASSOCIATED WITH OR LINKED TO

    • Infertility
    • Testicular dysgenesis
    • Obesity
    • Asthma
    • Allergies
    • Long term ADD in children
    • Derailing aspects of brain development
    • Alter thyroid function
    • Pregnant women using perfume have 167% higher urine concentrations of phthalates
    • Mothers and Breastmilk – 50% of Canadian mothers had phthalates in their breastmilk and pass it on to their children

    WATER AND PHTHALATES

    • 38% raw water had amounts
    • 29% of drinking water had amounts
    • DEHPn found at 1680 ng/l in bottled water

    BPA and BPS

    • BPA does not mean BPS free
    • List of Acronyms to avoid: BPAF, BPB, BPF, BPS
    • These exhibit anti-androgenic effects similar to or greater than BPA (Anti Male Hormone)

    WHAT ARE THEY

  • BPA’s are lipophilic or fat loving – which is true of all estrogenics – the more fat you have the likelier the chance your body will hold onto estrogenics
  • BPA strongly estrogenic in low doses

    • EFFECTS

    • Causes hyperactivity in children
    • BPA accelerates aging by outcompeting natural estrogen

    BPA disrupts glucose transport in the bran, causing excess child adiposity. This is odd because the brain’s preferred source of energy is glucose

    EE2 – BIRTH CONTROL

    • 100 million women use birth control
    • 60% of all married women
    • Designed to mimic estrogen and stay in the body longer than natural estrogen

    LEGALITY

    • Legal in United States where minors (fewer than 18 years old) in 20 states can take it
    • New cars have highest BP in air levels

    EXPOSURE

    • Fish exposed to EE2 – gonad deformations
    • Prenatal exposure to BPA may cause children with higher levels of anxiety depression aggression and hyperactivity
    • -biomarker for depression linked to BPA

    DES

    • Diethylslibestrol – known estrogenic (now banned but wasn’t always)
    • used to be prescribed as a drug
    • in utero effects of DES could lead to increased risk of depression in adult life

    GENERAL TAKEAWAYS

    • Eating fast foods for research increased certain estrogenics in the blood by 50% in some cases and over 40% in MOST cases
    • AVOID Fast Food is giving you massive amounts of estrogenics
    • Hydrophobic – estrogen hormones are absorbed most easily via the skin
    • Skin cannot block out bad oils and fats
    • Every cell has a lipid bilayer or coating. Easy for estrogenics to travel throughout the body
    • 2015 study 19 substances to be estrogenic were found in bodies/fat stores of humans: BPA, BPS, triclosan, parabens

    DRINKING ESTROGENICS - WATER

    • Water in plastic that gets hot creates far more estrogenic burden
    • Bottled water leachage
    • Microwaving also creates this issue

    DRINKING ESTROGENICS - MILK

    • MILK – leaching In from plastic milk containers
    • Cow Milk – non organic-17000 ng/l of APE
    • Goat milk – non organic 88,000 ng/l
    • 740,000 ng/l in blood of Holstein cows of ATRAZINE

    EATING ESTROGENICS - AVOID MUSSELS

    • Avoid Mussels
    • When a mussel is exposed to 5 estrogenics even for a short time, it will render them unable to reproduce
    • Phthalates found in mussels
    • EE2 found in mussels
    • BPA found in mussels
    • Atrazine found in mussels

    EFFECTS

    • Intersex changes
    • Decreases in essential fatty acids
    • Changes in glucose metabolism
    • Reduction in overall mussel reproduction (infertility)

    DAIRY AND BEEF

    • If the animal is exposed to estrogenics and you eat the animal, then you absorb all of the estrogenics
    • GRASS FED ONLY
    • NO CORN
    • NO GRAINS
    • NO ANTIBIOTICS

    REMOVING ESTROGENICS FROM YOUR BODY

    • EXERCISE - Removes fat and visceral fat
    • Fasting - Burns excess fat where estrogenics are stores

    THC AND ESTROGENICS

    • THC is stored in rodent GONAD fat at higher concentrations than in other organs such as the liver brain lungs or fatty tissues
    • Natural UNSELECTION of fertile age groups
    • THC found in bodies fat cells 77 days after exposure
    • Fat survives in the body for 1.5 years

    FAT AND ESTROGENICS

    • Estrogenics cause more fat growth
    • estrogenics are stored in fat
    • 1990 – 10% Americans were obese
    • 2000 – 20% Americans were obese
    • 2010 – 30% Americans were obese
    • In line with estrogenics in our environment
    • EU obesity rates are 50% what they are in the US
    • Not causal, but the parallels are telling

    DEPRESSION AND ESTROGENICS

    • Obesity is caused with depression
    • Estrogenics lead to obesity
    • Estrogenics leads to depression
    • NOT CAUSAL BECAUSE ITS HARD TO ACTUALLY STUDY – BUT TELLIN
    • Not only bc of body image
    • Chemical and hormonal imbalance
    • Phthalates have been associated w depression
    • BPA linked with depression

    ESTROGENICS AND SUICIDE

    • Women who take oral contraceptic have higher incidence of suicide
    • 45000 british women who committed suicide. Over 50% of them were oral contraceptive users.
    • 40 year study
    • Not causal, but tellin

    INDIA / SUICIDE

    • Within farming profession
    • Over 15000 per year among farmers
    • Skyrocketing chemical spraying
    • Is it just socioeconomic?
    • Farmers cannot compete in the chemical race with natural farming, so they are forced to use chemicals…but at what cost?
    • Atrazine in Delhi water was 3400 ng/l
    • EPA in USA allows 3000ng/l which is liberal
    • EU approves 0
    • Highest sample found was 17,300ng/l
    • Delhi is very farm from crops and farms

    ESTROGENICS AND LOW TESTOSTERONE

    • Many important behaviors connected to Estrogen and Testosterone interplay and the brain cell rearrangement that follows
    • This is called neuroplasticity (PORN)
    • Brain cells have E and T receptors
    • Estrogen and Testosterone are steroid hormones derived from cholesterol
    • Hormones are created in one cell or area and affect a different cell or area
    • Cholesterol is key to bodys ability to create steroid hormones
    • Testosterone has been reducing for a long time…BUT
    • Drastically over the last 40-50 years…all while estrognics have been rampant in our environment
    • 1940’s T levels were DOUBLE where they are now

    Testosterone Affects

  • Sexual desire
  • Bone density
  • Muscle mass
  • Strength
  • Adipose tissue distribution
  • Mood
  • Energy
  • Psychological well-being
  • Testosterone levels reflect your ALIVENESS

    • OTHER CAUSES of Low Testosterone

    • Indoor dwelling
    • Not enough sunlight
    • Not enough exercise
    • Sedentary jobs